Philip Sager: search on Z-Library

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1

Scientific white paper on concentration-QTc modeling

Garnett, Christine, Bonate, Peter L., Dang, Qianyu, Ferber, Georg, Huang, Dalong, Liu, Jiang, Mehrotra, Devan, Riley, Steve, Sager, Philip, Tornoe, Christoffer, Wang, Yaning

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2017

Language:

english

File:

PDF, 944 KB

english, 2017

2

Evolution of strategies to improve preclinical cardiac safety testing

Gintant, Gary, Sager, Philip T., Stockbridge, Norman

Journal:

Nature Reviews Drug Discovery

Year:

2016

Language:

english

File:

PDF, 510 KB

english, 2016

3

Long-Term Efficacy and Safety of Rosuvastatin 40 mg in Patients With Severe Hypercholesterolemia

Evan A. Stein, John Amerena, Christie M. Ballantyne, Edmund Brice, Michel Farnier, Robert M. Guthrie, Dror Harats, Patrick T.S. Ma, Florence Le Maulf, Helena Melezínková, Alex Gold, Philip Sager

Journal:

The American Journal of Cardiology

Year:

2007

Language:

english

File:

PDF, 341 KB

english, 2007

4

Atrial Fibrillation, Congestive Heart Failure, and the Middle Cerebral Artery

Ameriso, Sebastian F., Sager, Philip, Fisher, Mark

Journal:

Journal of Neuroimaging

Year:

1992

Language:

english

File:

PDF, 936 KB

english, 1992

5

Comparison of Effectiveness of Rosuvastatin Versus Atorvastatin on the Achievement of Combined C-Reactive Protein (

D. John Betteridge, J. Martin Gibson, Philip T. Sager

Journal:

The American Journal of Cardiology

Year:

2007

Language:

english

File:

PDF, 128 KB

english, 2007

6

Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: Efficacy and safety of ezetimibe co-administered with atorvastatin

Evan Stein, Steen Stender, Pedro Mata, Philip Sager, Damien Ponsonnet, Lorenzo Melani, Leslie Lipka, Ramachandran Suresh, Darbie MacCubbin, Enrico Veltri

Journal:

American Heart Journal

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

7

Long-Term Efficacy of Amiodarone for the Maintenance of Normal Sinus Rhythm in Patients With Refractory Atrial Fibrillation or Flutter

Chun, Sung H., Sager, Philip T., Stevenson, William G., Nademanee, Koonlawee, Middlekauff, Holly R., Singh, Bramah N.

Journal:

The American Journal of Cardiology

Year:

1995

Language:

english

File:

PDF, 540 KB

english, 1995

8

Correction to: Scientific white paper on concentration-QTc modeling

Garnett, Christine, Bonate, Peter L., Dang, Qianyu, Ferber, Georg, Huang, Dalong, Liu, Jiang, Mehrotra, Devan, Riley, Steve, Sager, Philip, Tornoe, Christoffer, Wang, Yaning

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2018

Language:

english

File:

PDF, 334 KB

english, 2018

9

Examining the Relationship Between Parent and Child Psychopathology in Treatment-Seeking Veterans

Zalta, Alyson K., Bui, Eric, Karnik, Niranjan S., Held, Philip, Laifer, Lauren M., Sager, Julia C., Zou, Denise, Rauch, Paula K., Simon, Naomi M., Pollack, Mark H., Ohye, Bonnie

Journal:

Child Psychiatry & Human Development

Year:

2017

Language:

english

File:

PDF, 713 KB

english, 2017

10

Differences in efficacy of monepantel, derquantel and abamectin against multi-resistant nematodes of sheep

Ronald Kaminsky, Beatrice Bapst, Philip A. Stein, Guenther A. Strehlau, Brooke A. Allan, Barry C. Hosking, Peter F. Rolfe, Heinz Sager

Journal:

Parasitology Research

Year:

2011

Language:

english

File:

PDF, 107 KB

english, 2011

11

Pentamidine-induced torsade de pointes

Abraham Gonzalez, Philip T. Sager, Bisher Akil, Shahbudin H. Rahimtoola, Anil K. Bhandari

Journal:

American Heart Journal

Year:

1991

Language:

english

File:

PDF, 842 KB

english, 1991

12

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

Kotze, Andrew C., Hunt, Peter W., Skuce, Philip, von Samson-Himmelstjerna, Georg, Martin, Richard J., Sager, Heinz, Krücken, Jürgen, Hodgkinson, Jane, Lespine, Anne, Jex, Aaron R., Gilleard, John S.,

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2014

Language:

english

File:

PDF, 2.16 MB

english, 2014

13

Comparative analysis of the influence of clinical factors including BMI on adalimumab and infliximab trough levels

Bond, Ashley, Asher, Rebecca, Jackson, Richard, Sager, Khalid, Martin, Kate, Kneebone, Andrew, Philips, Suzannah, Taylor, William, Subramanian, Sreedhar

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2016

Language:

english

File:

PDF, 172 KB

english, 2016

14

Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies

Mendzelevski, Boaz, Ferber, Georg, Janku, Filip, Li, Bob T., Sullivan, Ryan J., Welsch, Dean, Chi, Wei, Jackson, Jeanne, Weng, Onglee, Sager, Philip T.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

15

Atrial Fibrillation: Antiarrhythmic Therapy Versus Rate Control With Antithrombotic Therapy

Philip T. Sager MD

Journal:

The American Journal of Cardiology

Year:

1997

Language:

english

File:

PDF, 159 KB

english, 1997

16

Grognostic significance of programmed ventricular stimulation in patients surviving complicated acute myocardial infarction: A prospective study

Anil K. Bhandari, Josef Widerhorn, Philip T. Sager, Cheryl Leon, Hong Robert, Adam Kotlewski, James Hackett, Shahbudin H. Rahimtoola

Journal:

American Heart Journal

Year:

1992

Language:

english

File:

PDF, 1.09 MB

english, 1992

17

Antiarrhythmic drug exacerbation of ventricular tachycardia inducibility during electrophysiologic study

Philip T. Sager, Robin A. Perlmutter, Lynda E. Rosenfeld, William P. Batsford

Journal:

American Heart Journal

Year:

1992

Language:

english

File:

PDF, 934 KB

english, 1992

18

Electrophysiologic effects of thrombolytic therapy in patients with a transmural anterior myocardial infarction complicated by left ventricular aneurysm formation

Philip T. Sager, Robin A. Perlmutter, Lynda E. Rosenfeld, Craig A. McPherson, Frans J.Th. Wackers, William P. Batsford

Journal:

Journal of the American College of Cardiology

Year:

1988

Language:

english

File:

PDF, 441 KB

english, 1988

19

Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: A dose-response study

Kenneth A. Ellenbogen, Bruce S. Stambler, Mark A. Wood, Philip T. Sager, Robert C. Wesley Jr., Marc D. Meissner, Robert G. Zoble, Linda K. Wakefield, Kimberly T. Perry, James T. Vanderlugtt, Ibutilide

Journal:

Journal of the American College of Cardiology

Year:

1996

Language:

english

File:

PDF, 879 KB

english, 1996

20

Clinical Evaluation of QT/QTc Prolongation and Proarrhythmic Potential for Nonantiarrhythmic Drugs: The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use E14 Guideline

Darpo, Borje, Nebout, Thierry, Sager, Philip T.

Journal:

Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 103 KB

english, 2006

21

The Cardiac Safety Research Consortium enters its second decade: An invitation to participate

Turner, J. Rick, Kowey, Peter R., Rodriguez, Ignacio, Cabell, Christopher H., Gintant, Gary, Green, Cynthia L., Kunz, Barbara Lopez, Mortara, Justin, Sager, Philip T., Stockbridge, Norman, Wright, The

Journal:

American Heart Journal

Year:

2016

Language:

english

File:

PDF, 221 KB

english, 2016

22

Influence of Meals and Glycemic Changes on QT Interval Dynamics

Cirincione, Brenda, Sager, Philip T., Mager, Donald E.

Journal:

Journal of Clinical Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.61 MB

english, 2017

23

Correction: Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

Vicente, Jose, Johannesen, Lars, Hosseini, Meisam, Mason, Jay W., Sager, Philip T., Pueyo, Esther, Strauss, David G.

Journal:

Year:

2018

Language:

english

File:

PDF, 213 KB

english, 2018

24

Dual antegrade his bundle pathways with alternating bundle branch block

Rafique Ahmed, Philip T. Sager, Mahnaz Behboodikah, Bramah N. Singh

Journal:

American Heart Journal

Year:

1993

Language:

english

File:

PDF, 365 KB

english, 1993

25

Comparison of ezetimibe plus simvastatin versus simvastatin monotherapy on atherosclerosis progression in familial hypercholesterolemia: Design and rationale of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial

John J.P. Kastelein, Philip T. Sager, Eric de Groot, Enrico Veltri

Journal:

American Heart Journal

Year:

2005

Language:

english

File:

PDF, 270 KB

english, 2005

26

Consistency in Efficacy and Safety of Ezetimibe Coadministered with Statins for Treatment of Hypercholesterolemia in Women and Men

Bennett, Susan, Sager, Philip, Lipka, Leslie, Melani, Lorenzo, Suresh, Ramachandran, Veltri, Enrico

Journal:

Journal of Women's Health

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

27

Mechanistic Model-Informed Proarrhythmic Risk Assessment of Drugs: Review of the ‘CiPA' Initiative and Design of a Prospective Clinical Validation Study

Vicente, Jose, Zusterzeel, Robbert, Johannesen, Lars, Mason, Jay, Sager, Philip, Patel, Vikram, Matta, Murali K, Li, Zhihua, Liu, Jiang, Garnett, Christine, Stockbridge, Norman, Zineh, Issam, Strauss,

Journal:

Clinical Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

28

Drug-induced Proarrhythmia and Torsade de Pointes: A Primer for Students and Practitioners of Medicine and Pharmacy

Turner, J. Rick, Rodriguez, Ignacio, Mantovani, Emily, Gintant, Gary, Kowey, Peter R., Klotzbaugh, Ralph J., Prasad, Krishna, Sager, Philip T., Stockbridge, Norman, Strnadova, Colette

Journal:

Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 382 KB

english, 2018

29

Solithromycin, a novel macrolide, does not prolong cardiac repolarization: a randomized, three-way crossover study in healthy subjects

Darpo, Borje, Sager, Philip T., Fernandes, Prabhavathi, Jamieson, Brian D., Keedy, Kara, Zhou, Meijian, Oldach, David

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2016

Language:

english

File:

PDF, 324 KB

english, 2016

30

Rapid self-terminating ventricular tachycardia induced during electrophysiologic study: A prospective evaluation

Philip T. Sager, Robin A. Perlmutter, Lynda E. Rosenfeld, Craig A. McPherson, William P. Batsford

Journal:

Journal of the American College of Cardiology

Year:

1989

Language:

english

File:

PDF, 768 KB

english, 1989

31

Effects of amiodarone, sematilide, and sotalol on QT dispersion

Guanggen Cui, Luyi Sen, Philip Sager, Parveen Uppal, Bramah N. Singh

Journal:

The American Journal of Cardiology

Year:

1994

Language:

english

File:

PDF, 646 KB

english, 1994

32

Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting

Strauss, David G., Gintant, Gary, Li, Zhihua, Wu, Wendy, Blinova, Ksenia, Vicente, Jose, Turner, J. Rick, Sager, Philip T.

Journal:

Therapeutic Innovation & Regulatory Science

Year:

2018

Language:

english

File:

PDF, 348 KB

english, 2018

33

Electrophysiological Evaluation of Moricizine in Patients with Sustained Ventricular Tachyarrhythmias: Low Efficacy and High Incidence of Proarrhythmia

ANIL K. BHANDARI, ROBERT LERMAN, STEVEN EHRLICH, PHILIP SAGER, CHERYL LEON, JOSEPH WIDERHORN, DAVID S. CANNOM

Journal:

Pacing and Clinical Electrophysiology

Year:

1993

Language:

english

File:

PDF, 4.03 MB

english, 1993

34

Modulation of antiarrhythmic drug effects by beta-adrenergic sympathetic stimulation

Philip T. Sager

Journal:

The American Journal of Cardiology

Year:

1998

Language:

english

File:

PDF, 351 KB

english, 1998

35

Rapid Conversion of Persistent Atrial Fibrillation to Sinus Rhythm by Intravenous AZD7009

Geller, J. Christoph, Egstrup, Kenneth, Kulakowski, Piotr, Rosenqvist, Mårten, Jansson, Maria Aunes, Berggren, Anders, Edvardsson, Nils, Sager, Philip, Crijns, Harry J.

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 932 KB

english, 2009

36

The Cardiac Safety Research Consortium electrocardiogram warehouse: Thorough QT database specifications and principles of use for algorithm development and testing

Paul Kligfield, Cynthia L. Green, Justin Mortara, Philip Sager, Norman Stockbridge, Michael Li, Joanne Zhang, Samuel George, Ignacio Rodriguez, Daniel Bloomfield, Mitchell W. Krucoff

Journal:

American Heart Journal

Year:

2010

Language:

english

File:

PDF, 212 KB

english, 2010

37

Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QT c interval in healthy subjects

Darpö, Börje, Philip, Sager, MacConell, Leigh, Cirincione, Brenda, Mitchell, Malcolm, Han, Jenny, Huang, Wenying, Malloy, Jaret, Schulteis, Christine, Shen, Larry, Porter, Lisa

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

38

Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm

Stambler, Bruce S., Dorian, Paul, Sager, Philip T., Wight, Douglas, Douville, Philippe, Potvin, Diane, Shamszad, Pirouz, Haberman, Ronald J., Kuk, Richard S., Lakkireddy, Dhanunjaya R., Teixeira, Jose

Journal:

Journal of the American College of Cardiology

Year:

2018

Language:

english

File:

PDF, 579 KB

english, 2018

39

Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium

Sager, Philip T., Gintant, Gary, Turner, J. Rick, Pettit, Syril, Stockbridge, Norman

Journal:

American Heart Journal

Year:

2014

Language:

english

File:

PDF, 555 KB

english, 2014

40

Computerized Extraction of Electrocardiograms From Continuous 12-Lead Holter Recordings Reduces Measurement Variability in a Thorough QT Study

George, Samuel, Rodriguez, Ignacio, Ipe, David, Sager, Philip T., Gussak, Ihor, Vajdic, Branislav

Journal:

Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 312 KB

english, 2012

41

MULTIPLE STRESSORS AND SALAMANDERS: EFFECTS OF AN HERBICIDE, FOOD LIMITATION, AND HYDROPERIOD

Rohr, Jason R., Elskus, Adria A., Shepherd, Brian S., Crowley, Philip H., McCarthy, Thomas M., Niedzwiecki, John H., Sager, Tyler, Sih, Andrew, Palmer, Brent D.

Journal:

Ecological Applications

Year:

2004

Language:

english

File:

PDF, 264 KB

english, 2004

42

Centralized adjudication of cardiovascular end points in cardiovascular and noncardiovascular pharmacologic trials: A report from the Cardiac Safety Research Consortium

Seltzer, Jonathan H., Turner, J. Rick, Geiger, Mary Jane, Rosano, Giuseppe, Mahaffey, Kenneth W., White, William B., Sabol, Mary Beth, Stockbridge, Norman, Sager, Philip T.

Journal:

American Heart Journal

Year:

2015

Language:

english

File:

PDF, 167 KB

english, 2015

43

Cardiovascular safety for once-weekly dulaglutide in type 2 diabetes: a pre-specified meta-analysis of prospectively adjudicated cardiovascular events

Ferdinand, Keith C., Botros, Fady T., Atisso, Charles M., Sager, Philip T.

Journal:

Cardiovascular Diabetology

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

44

Percutaneous transluminal angioplasty of the superficial femoral artery by retrograde catheterization via the popliteal artery

Knud Henrik Tønnesen, Philip Sager, Agnete Karle, Lars Henriksen, Bo Jørgensen

Journal:

CardioVascular and Interventional Radiology

Year:

1988

Language:

english

File:

PDF, 386 KB

english, 1988

45

Early clinical development: Evaluation of drug-induced torsades de pointes risk

Torbjorn Vik, Chris Pollard, Philip Sager

Journal:

Pharmacology & Therapeutics

Year:

2008

Language:

english

File:

PDF, 174 KB

english, 2008

46

The Potential Role of the J‐T peak Interval in Proarrhythmic Cardiac Safety: Current State of the Science From the American College of Clinical Pharmacology and the Cardiac Safety Research Consortium

Vicente, Jose, Strauss, David G., Upreti, Vijay V., Fossler, Michael J., Sager, Philip T., Noveck, Robert

Journal:

Journal of Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 436 KB

english, 2019

47

Lethal and sublethal effects of atrazine, carbaryl, endosulfan, and octylphenol on the streamside salamander (Ambystoma barbouri)

Jason R. Rohr, Adria A. Elskus, Brian S. Shepherd, Philip H. Crowley, Thomas M. McCarthy, John H. Niedzwiecki, Tyler Sager, Andrew Sih, Brent D. Palmer

Journal:

Environmental Toxicology and Chemistry

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

48

Effect of Short-Term Rosuvastatin Treatment on Estimated Glomerular Filtration Rate

Donald G. Vidt, Susan Harris, Fergus McTaggart, Marc Ditmarsch, Philip T. Sager, Jonathan M. Sorof

Journal:

The American Journal of Cardiology

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

49

Relation of pace mapping QRS configuration and conduction delay to ventricular tachycardia reentry circuits in human infarct scars

William G. Stevenson, Philip T. Sager, Paul D. Natterson, Leslie A. Saxon, Holly R. Middlekauff, Isaac Wiener

Journal:

Journal of the American College of Cardiology

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

50

Heterozygous familial hypercholesterolemia: Coadministration of ezetimibe plus atorvastatin

Vermaak, William, Pinto, Xavier, Ponsonnet, Damien, Sager, Philip, Lipka, Leslie, Suresh, Ramachandran, Veltri, Enrico

Journal:

Journal of the American College of Cardiology

Year:

2003

Language:

english

File:

PDF, 188 KB

english, 2003

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